| | | |
| Overexpression of schizophrenia susceptibility factor human complement C4A promotes excessive synaptic loss and behavioral changes in mice | Yilmaz M, Yalcin E, Presumey J, Aw E, Ma M, Whelan CW, Stevens B, McCarroll SA, Carroll MC | Nature Neuroscience | 2020 |
Microglial responses to peripheral type 1 interferon
| Ernest Aw, Yingying Zhang, Michael Carroll. | Journal of Neuroinflammation | 2020 |
| An Ultrahigh-Affinity Complement C4b-Specific Nanobody Inhibits In Vivo Assembly of the Classical Pathway Proconvertase | Zarantonello A, Presumey J, Simoni L, Yalcin E, Fox R, Hansen A, Olesen HG, Thiel S, Johnson MB, Stevens B, Laursen NS, Carroll MC, Andersen GR. | Journal of Immunology | 2020 |
| Complement C4A Regulates Autoreactive B Cells in Murine Lupus | Léa Simoni, Jessy Presumey, Cees E van der Poel , Carlos Castrillon , Sarah E Chang , Paul J Utz , Michael C Carroll. | Cell Reports | 2020 |
| | | |
| Protection against influenza infection requires early recognition by inflammatory dendritic cells through C-type lectin receptor SIGN-R1. | Palomino-Segura M, Perez L, Farsakoglu Y, Virgilio T, Latino I, D'Antuono R, Chatziandreou N, Pizzagalli DU, Wang G, García-Sastre A, Sallusto F, Carroll MC, Neyrolles O, Gonzalez SF. | Nature Microbiology | 2019 |
| Follicular Dendritic Cells Modulate Germinal Center B Cell Diversity through FcγRIIB. | van der Poel CE, Bajic G, Macaulay CW, van den Broek T, Ellson CD, Bouma G, Victora GD, Degn SE, Carroll MC | Cell Reports | 2019 |
| Mechanosensing by Peyer's patch stroma regulates lymphocyte migration and mucosal antibody responses | Chang JE, Buechler MB, Gressier E, Turley SJ, Carroll MC | Nature immunology | 2019 |
| Capturing change in clonal composition amongst single mouse germinal centers | Firl DJ, Degn SE, Padera T, Carroll MC | Elife | 2018 |
| B cell tolerance to epidermal ribonuclear-associated neo-autoantigen in vivo | Degn SE, Alicot E, Carroll MC | Clinical and experimental immunology | 2018 |
| Clonal Evolution of Autoreactive Germinal Centers | Degn SE, van der Poel CE, Firl DJ, Ayoglu B, Al Qureshah FA, Bajic G, Mesin L, Reynaud CA, Weill JC, Utz PJ, Victora GD, Carroll MC | Cell | 2017 |
| Complement System in Neural Synapse Elimination in Development and Disease | Presumey J, Bialas AR, Carroll MC | Advances in immunology | 2017 |
| Untangling Fc and complement receptors to kill tumors | van der Poel CE, Carroll MC | Nature immunology | 2017 |
| C3d regulates immune checkpoint blockade and enhances antitumor immunity | Platt JL, Silva I, Balin SJ, Lefferts AR, Farkash E, Ross TM, Carroll MC, Cascalho M | JCI insight | 2017 |
| Macrophage Death following Influenza Vaccination Initiates the Inflammatory Response that Promotes Dendritic Cell Function in the Draining Lymph Node | Chatziandreou N, Farsakoglu Y, Palomino-Segura M, D'Antuono R, Pizzagalli DU, Sallusto F, Lukacs-Kornek V, Uguccioni M, Corti D, Turley SJ, Lanzavecchia A, Carroll MC, Gonzalez SF | Cell reports | 2017 |
| Follicular Dendritic Cell Activation by TLR Ligands Promotes Autoreactive B Cell Responses | Das A, Heesters BA, Bialas A, O'Flynn J, Rifkin IR, Ochando J, Mittereder N, Carlesso G, Herbst R, Carroll MC | Immunity | 2017 |
| Follicular Dendritic Cell Isolation and Loading of Immune Complexes | Heesters BA, Van der Poel CE, Carroll MC | Methods in molecular biology | 2017 |
| Antigen Presentation to B Cells | Heesters BA, van der Poel CE, Das A, Carroll MC | Trends in immunology | 2016 |
| The Role of Dendritic Cells in S. pneumoniae Transport to Follicular Dendritic Cells | Heesters BA, Carroll MC | Cell reports | 2016 |
| Cutting Edge: Marginal Zone Macrophages Regulate Antigen Transport by B Cells to the Follicle in the Spleen via CD21 | Prokopec KE, Georgoudaki AM, Sohn S, Wermeling F, Grönlund H, Lindh E, Carroll MC, Karlsson MC | Journal of immunology | 2016 |
| Prevention of intestinal ischemia-reperfusion injury in humanized mice | Sheu EG, Wakatsuki K, Oakes S, Carroll MC, Moore FD Jr | Surgery | 2016 |
| Schizophrenia risk from complex variation of complement component 4 | Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K, Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE, Daly MJ, Carroll MC, Stevens B, McCarroll SA | Nature | 2016 |
| Natural IgM Blockade Limits Infarct Expansion and Left Ventricular Dysfunction in a Swine Myocardial Infarct Model | Sihag S, Haas MS, Kim KM, Guerrero JL, Beaudoin J, Alicot EM, Schuerpf F, Gottschall JD, Puro RJ, Madsen JC, Sachs DH, Newman W, Carroll MC, Allan JS | Circulation, Cardiovascular interventions | 2016 |
| Follicular Dendritic Cells Retain Infectious HIV in Cycling Endosomes | Heesters BA, Lindqvist M, Vagefi PA, Scully EP, Schildberg FA, Altfeld M, Walker BD, Kaufmann DE, Carroll MC | PLoS pathogens | 2015 |
| Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR | Kubagawa H, Carroll MC, Jacob CO, Lang KS, Lee KH, Mak T, McAndrews M, Morse HC 3rd, Nolan GP, Ohno H, Richter GH, Seal R, Wang JY, Wiestner A, Coligan JE | Journal of immunology | 2015 |
| The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture | Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ | Nature immunology | 2015 |
| Do follicular dendritic cells regulate lupus-specific B cells? | Heesters BA, Das A, Chatterjee P, Carroll MC | Molecular immunology | 2014 |
| B cell homeostasis and follicle confines are governed by fibroblastic reticular cells | Cremasco V, Woodruff MC, Onder L, Cupovic J, Nieves-Bonilla JM, Schildberg FA, Chang J, Cremasco F, Harvey CJ, Wucherpfennig K, Ludewig B, Carroll MC, Turley SJ | Nature immunology | 2014 |
| L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials | Zhao F, Heesters BA, Chiu I, Gao Y, Shi J, Zhou N, Carroll MC, Xu B | Organic & biomolecular chemistry | 2014 |
| Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine | Woodruff MC, Heesters BA, Herndon CN, Groom JR, Thomas PG, Luster AD, Turley SJ, Carroll MC | The Journal of experimental medicine | 2014 |
| B cells regulate CD4+ T cell responses to papain following B cell receptor-independent papain uptake | Dwyer DF, Woodruff MC, Carroll MC, Austen KF, Gurish MF | Journal of immunology | 2014 |
| Follicular dendritic cells: dynamic antigen libraries | Heesters BA, Myers RC, Carroll MC | Nature reviews, Immunology | 2014 |
| Bacteria activate sensory neurons that modulate pain and inflammation | Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ | Nature | 2013 |
| Contextual analysis of immunological response through whole-organ fluorescent imaging | Woodruff MC, Herndon CN, Heesters BA, Carroll MC | Lymphatic research and biology | 2013 |
| Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner | Chatterjee P, Agyemang AF, Alimzhanov MB, Degn S, Tsiftsoglou SA, Alicot E, Jones SA, Ma M, Carroll MC | European journal of immunology | 2013 |
| A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model | Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T | Cell reports | 2013 |
| Endocytosis and recycling of immune complexes by follicular dendritic cells enhances B cell antigen binding and activation | Heesters BA, Chatterjee P, Kim YA, Gonzalez SF, Kuligowski MP, Kirchhausen T, Carroll MC | Immunity | 2013 |
| Cochlin produced by follicular dendritic cells promotes antibacterial innate immunity | Py BF, Gonzalez SF, Long K, Kim MS, Kim YA, Zhu H, Yao J, Degauque N, Villet R, Ymele-Leki P, Gadjeva M, Pier GB, Carroll MC, Yuan J | Immunity | 2013 |
| Protective anti-inflammatory effect of ADAMTS13 on myocardial ischemia/reperfusion injury in mice | De Meyer SF, Savchenko AS, Haas MS, Schatzberg D, Carroll MC, Schiviz A, Dietrich B, Rottensteiner H, Scheiflinger F, Wagner DD | Blood | 2012 |
| Podoplanin-rich stromal networks induce dendritic cell motility via activation of the C-type lectin receptor CLEC-2 | Acton SE, Astarita JL, Malhotra D, Lukacs-Kornek V, Franz B, Hess PR, Jakus Z, Kuligowski M, Fletcher AL, Elpek KG, Bellemare-Pelletier A, Sceats L, Reynoso ED, Gonzalez SF, Graham DB, Chang J, Peters A, Woodruff M, Kim YA, Swat W, Morita T, Kuchroo V, Carroll MC, Kahn ML, Wucherpfennig KW, Turley SJ | Immunity | 2012 |
| Regulation of humoral immunity by complement | Carroll MC, Isenman DE | Immunity | 2012 |
| SAP expression in invariant NKT cells is required for cognate help to support B-cell responses | Detre C, Keszei M, Garrido-Mesa N, Kis-Toth K, Castro W, Agyemang AF, Veerapen N, Besra GS, Carroll MC, Tsokos GC, Wang N, Leadbetter EA, Terhorst C | Blood | 2012 |
| Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia | Fu H, Liu B, Frost JL, Hong S, Jin M, Ostaszewski B, Shankar GM, Costantino IM, Carroll MC, Mayadas TN, Lemere CA | Glia | 2012 |
| Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks | Malhotra D, Fletcher AL, Astarita J, Lukacs-Kornek V, Tayalia P, Gonzalez SF, Elpek KG, Chang SK, Knoblich K, Hemler ME, Brenner MB, Carroll MC, Mooney DJ, Turley SJ | Nature immunology | 2012 |
| THE ROLE OF SPECIFIC IgG AND COMPLEMENT IN COMBATING A PRIMARY MUCOSAL INFECTION OF THE GUT EPITHELIUM | Belzer C, Liu Q, Carroll MC, Bry L | European journal of microbiology & immunology | 2011 |
| Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation | Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK | Immunity | 2011 |
| Requirement for complement in antibody responses is not explained by the classic pathway activator IgM | Rutemark C, Alicot E, Bergman A, Ma M, Getahun A, Ellmerich S, Carroll MC, Heyman B | Proceedings of the National Academy of Sciences of the United States of America | 2011 |
| Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cells | McCloskey ML, Curotto de Lafaille MA, Carroll MC, Erlebacher A | The Journal of experimental medicine | 2011 |
| Trafficking of B cell antigen in lymph nodes | Gonzalez SF, Degn SE, Pitcher LA, Woodruff M, Heesters BA, Carroll MC | Annual review of immunology | 2011 |
| B cell subsets contribute to renal injury and renal protection after ischemia/reperfusion | Renner B, Strassheim D, Amura CR, Kulik L, Ljubanovic D, Glogowska MJ, Takahashi K, Carroll MC, Holers VM, Thurman JM | Journal of immunology | 2010 |
| Complement-dependent transport of antigen into B cell follicles | Gonzalez SF, Lukacs-Kornek V, Kuligowski MP, Pitcher LA, Degn SE, Turley SJ, Carroll MC | Journal of immunology | 2010 |
| Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction | Haas MS, Alicot EM, Schuerpf F, Chiu I, Li J, Moore FD, Carroll MC | Cardiovascular research | 2010 |
| Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes | Gonzalez SF, Lukacs-Kornek V, Kuligowski MP, Pitcher LA, Degn SE, Kim YA, Cloninger MJ, Martinez-Pomares L, Gordon S, Turley SJ, Carroll MC | Nature immunology | 2010 |
| The role of innate immunity in B cell acquisition of antigen within LNs | Gonzalez SF, Kuligowski MP, Pitcher LA, Roozendaal R, Carroll MC | Advances in immunology | 2010 |
| Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice | Chiu IM, Phatnani H, Kuligowski M, Tapia JC, Carrasco MA, Zhang M, Maniatis T, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 2009 |
| Uncoupling CD21 and CD19 of the B-cell coreceptor | Barrington RA, Schneider TJ, Pitcher LA, Mempel TR, Ma M, Barteneva NS, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 2009 |
| Restoration of skeletal muscle ischemia-reperfusion injury in humanized immunodeficient mice | Sheu EG, Oakes SM, Ahmadi-Yazdi C, Afnan J, Carroll MC, Moore FD Jr | Surgery | 2009 |
| B cell acquisition of antigen in vivo | Gonzalez SF, Pitcher LA, Mempel T, Schuerpf F, Carroll MC | Current opinion in immunology | 2009 |
| Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination | Guttormsen HK, Stuart LM, Shi L, Carroll MC, Chen J, Kasper DL, Ezekowitz RA, Takahashi K | Clinical immunology | 2009 |
| Conduits mediate transport of low-molecular-weight antigen to lymph node follicles | Roozendaal R, Mempel TR, Pitcher LA, Gonzalez SF, Verschoor A, Mebius RE, von Andrian UH, Carroll MC | Immunity | 2009 |
| Complement and natural antibody are required in the long-term memory response to influenza virus | Fernandez Gonzalez S, Jayasekera JP, Carroll MC | Vaccine | 2008 |
| Complement and humoral immunity | Carroll MC | Vaccine | 2008 |
| T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS | Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TK, Brown RH Jr, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 2008 |
| Human natural IgM can induce ischemia/reperfusion injury in a murine intestinal model | Zhang M, Alicot EM, Carroll MC | Molecular immunology | 2008 |
| Complement C3 deficiency leads to accelerated amyloid beta plaque deposition and neurodegeneration and modulation of the microglia/macrophage phenotype in amyloid precursor protein transgenic mice | Maier M, Peng Y, Jiang L, Seabrook TJ, Carroll MC, Lemere CA | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2008 |
| Mannose binding lectin gene deficiency increases susceptibility to traumatic brain injury in mice | Yager PH, You Z, Qin T, Kim HH, Takahashi K, Ezekowitz AB, Stahl GL, Carroll MC, Whalen MJ | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 2008 |
| Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4 | You Z, Yang J, Takahashi K, Yager PH, Kim HH, Qin T, Stahl GL, Ezekowitz RA, Carroll MC, Whalen MJ | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism | 2007 |
| Natural IgM-mediated innate autoimmunity: a new target for early intervention of ischemia-reperfusion injury | Zhang M, Carroll MC | Expert opinion on biological therapy | 2007 |
| The presence of MOMA-2+ macrophages in the outer B cell zone and protection of the splenic micro-architecture from LPS-induced destruction depend on secreted IgM | Fischer MB, Rüger B, Vaculik C, Becherer A, Wadsak W, Yanagida G, Losert UM, Chen J, Carroll MC, Eibl MM | European journal of immunology | 2007 |
| Complement receptors CD21 and CD35 in humoral immunity | Roozendaal R, Carroll MC | Immunological reviews | 2007 |
| Circulating C3 is necessary and sufficient for induction of autoantibody-mediated arthritis in a mouse model | Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D | Arthritis and rheumatism | 2007 |
| Follicular exclusion of autoreactive B cells requires FcgammaRIIb | Paul E, Nelde A, Verschoor A, Carroll MC | International immunology | 2007 |
| Natural antibody and complement mediate neutralization of influenza virus in the absence of prior immunity | Jayasekera JP, Moseman EA, Carroll MC | Journal of virology | 2007 |
| Innate response to self-antigen significantly exacerbates burn wound depth | Suber F, Carroll MC, Moore FD Jr | Proceedings of the National Academy of Sciences of the United States of America | 2007 |
| B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells | Shimizu I, Kawahara T, Haspot F, Bardwell PD, Carroll MC, Sykes M | Blood | 2007 |
| Natural antibody mediated innate autoimmune response | Zhang M, Carroll MC | Molecular immunology | 2007 |
| The differing roles of the classical and mannose-binding lectin complement pathways in the events following skeletal muscle ischemia-reperfusion | Chan RK, Ibrahim SI, Takahashi K, Kwon E, McCormack M, Ezekowitz A, Carroll MC, Moore FD Jr, Austen WG Jr | Journal of immunology | 2006 |
| Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury | Zhang M, Takahashi K, Alicot EM, Vorup-Jensen T, Kessler B, Thiel S, Jensenius JC, Ezekowitz RA, Moore FD, Carroll MC | Journal of immunology | 2006 |
| T cell-independent and T cell-dependent immunoglobulin G responses to polyomavirus infection are impaired in complement receptor 2-deficient mice | Szomolanyi-Tsuda E, Seedhom MO, Carroll MC, Garcea RL | Virology | 2006 |
| Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis | Banda NK, Thurman JM, Kraus D, Wood A, Carroll MC, Arend WP, Holers VM | Journal of immunology | 2006 |
| Involvement of NFAT1 in B cell self-tolerance | Barrington RA, Borde M, Rao A, Carroll MC | Journal of immunology | 2006 |
| Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells | Brockman MA, Verschoor A, Zhu J, Carroll MC, Knipe DM | Journal of virology | 2006 |
| The role of natural IgM in myocardial ischemia-reperfusion injury | Zhang M, Michael LH, Grosjean SA, Kelly RA, Carroll MC, Entman ML | Journal of molecular and cellular cardiology | 2006 |
| Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation | Taube C, Thurman JM, Takeda K, Joetham A, Miyahara N, Carroll MC, Dakhama A, Giclas PC, Holers VM, Gelfand EW | Proceedings of the National Academy of Sciences of the United States of America | 2006 |
| Emerging patterns in complement-mediated pathogen recognition | Roozendaal R, Carroll MC | Cell | 2006 |
| Transcriptional basis of lymphocyte tolerance | Borde M, Barrington RA, Heissmeyer V, Carroll MC, Rao A | Immunological reviews | 2006 |
| Attenuation of skeletal muscle reperfusion injury with intravenous 12 amino acid peptides that bind to pathogenic IgM | Chan RK, Verna N, Afnan J, Zhang M, Ibrahim S, Carroll MC, Moore FD Jr | Surgery | 2006 |
| Identification of the target self-antigens in reperfusion injury | Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC | The Journal of experimental medicine | 2006 |
| CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses | Barrington RA, Zhang M, Zhong X, Jonsson H, Holodick N, Cherukuri A, Pierce SK, Rothstein TL, Carroll MC | Journal of immunology | 2005 |
| Mast cell protease 5 mediates ischemia-reperfusion injury of mouse skeletal muscle | Abonia JP, Friend DS, Austen WG Jr, Moore FD Jr, Carroll MC, Chan R, Afnan J, Humbles A, Gerard C, Knight P, Kanaoka Y, Yasuda S, Morokawa N, Austen KF, Stevens RL, Gurish MF | Journal of immunology | 2005 |
| Defective B cell responses in the absence of SH2D1A | Morra M, Barrington RA, Abadia-Molina AC, Okamoto S, Julien A, Gullo C, Kalsy A, Edwards MJ, Chen G, Spolski R, Leonard WJ, Huber BT, Borrow P, Biron CA, Satoskar AR, Carroll MC, Terhorst C | Proceedings of the National Academy of Sciences of the United States of America | 2005 |
| Innate autoimmunity | Carroll MC, Holers VM | Advances in immunology | 2005 |
| A protective role for innate immunity in systemic lupus erythematosus | Carroll MC | Nature reviews, Immunology | 2004 |
| The complement system in regulation of adaptive immunity | Carroll MC | Nature immunology | 2004 |
| Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM | Austen WG Jr, Zhang M, Chan R, Friend D, Hechtman HB, Carroll MC, Moore FD Jr | Surgery | 2004 |
| The complement system in B cell regulation | Carroll MC | Molecular immunology | 2004 |
| Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury | Zhang M, Austen WG Jr, Chiu I, Alicot EM, Hung R, Ma M, Verna N, Xu M, Hechtman HB, Moore FD Jr, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 2004 |
| B cell receptor signal strength determines B cell fate | Casola S, Otipoby KL, Alimzhanov M, Humme S, Uyttersprot N, Kutok JL, Carroll MC, Rajewsky K | Nature immunology | 2004 |
| Germinal center checkpoints in B cell tolerance in 3H9 transgenic mice | Paul E, Lutz J, Erikson J, Carroll MC | International immunology | 2004 |
| T cell-independent somatic hypermutation in murine B cells with an immature phenotype | Mao C, Jiang L, Melo-Jorge M, Puthenveetil M, Zhang X, Carroll MC, Imanishi-Kari T | Immunity | 2004 |
| Myeloid C3 determines induction of humoral responses to peripheral herpes simplex virus infection | Verschoor A, Brockman MA, Gadjeva M, Knipe DM, Carroll MC | Journal of immunology | 2003 |
| Critical role of the complement system in group B streptococcus-induced tumor necrosis factor alpha release | Levy O, Jean-Jacques RM, Cywes C, Sisson RB, Zarember KA, Godowski PJ, Christianson JL, Guttormsen HK, Carroll MC, Nicholson-Weller A, Wessels MR | Infection and immunity | 2003 |
| A role for complement in feedback enhancement of antibody responses by IgG3 | Díaz de Ståhl T, Dahlstrom J, Carroll MC, Heyman B | The Journal of experimental medicine | 2003 |
| F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins | Basta M, Van Goor F, Luccioli S, Billings EM, Vortmeyer AO, Baranyi L, Szebeni J, Alving CR, Carroll MC, Berkower I, Stojilkovic SS, Metcalfe DD | Nature medicine | 2003 |
| The role of complement and natural antibody in intestinal ischemia-reperfusion injury | Austen WG Jr, Kobzik L, Carroll MC, Hechtman HB, Moore FD Jr | International journal of immunopathology and pharmacology | 2003 |
| Impaired antibody response to group B streptococcal type III capsular polysaccharide in C3- and complement receptor 2-deficient mice | Pozdnyakova O, Guttormsen HK, Lalani FN, Carroll MC, Kasper DL | Journal of immunology | 2003 |
| Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice | Gadjeva M, Verschoor A, Brockman MA, Jezak H, Shen LM, Knipe DM, Carroll MC | Journal of immunology | 2002 |
| Functional activity of natural antibody is altered in Cr2-deficient mice | Reid RR, Woodcock S, Shimabukuro-Vornhagen A, Austen WG Jr, Kobzik L, Zhang M, Hechtman HB, Moore FD Jr, Carroll MC | Journal of immunology | 2002 |
| B lymphocyte memory: role of stromal cell complement and FcgammaRIIB receptors | Barrington RA, Pozdnyakova O, Zafari MR, Benjamin CD, Carroll MC | The Journal of experimental medicine | 2002 |
| Anti-DNA autoreactivity in C4-deficient mice | Paul E, Pozdnyakova OO, Mitchell E, Carroll MC | European journal of immunology | 2002 |
| Redundant and alternative roles for activating Fc receptors and complement in an antibody-dependent model of autoimmune vitiligo | Trcka J, Moroi Y, Clynes RA, Goldberg SM, Bergtold A, Perales MA, Ma M, Ferrone CR, Carroll MC, Ravetch JV, Houghton AN | Immunity | 2002 |
| Immunoglobulin G monoclonal antibodies to Cryptococcus neoformans protect mice deficient in complement component C3 | Shapiro S, Beenhouwer DO, Feldmesser M, Taborda C, Carroll MC, Casadevall A, Scharff MD | Infection and immunity | 2002 |
| Arthritis critically dependent on innate immune system players | Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D | Immunity | 2002 |
| Complement C4 is protective for lupus disease independent of C3 | Einav S, Pozdnyakova OO, Ma M, Carroll MC | Journal of immunology | 2002 |
| Complement activation in factor D-deficient mice | Xu Y, Ma M, Ippolito GC, Schroeder HW Jr, Carroll MC, Volanakis JE | Proceedings of the National Academy of Sciences of the United States of America | 2001 |
| Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis | Welch TR, Frenzke M, Carroll MC, Witte DP | Clinical immunology | 2001 |
| The allogeneic T and B cell response is strongly dependent on complement components C3 and C4 | Marsh JE, Farmer CK, Jurcevic S, Wang Y, Carroll MC, Sacks SH | Transplantation | 2001 |
| Cutting edge: myeloid complement C3 enhances the humoral response to peripheral viral infection | Verschoor A, Brockman MA, Knipe DM, Carroll MC | Journal of immunology | 2001 |
| Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis | Han Y, Kozel TR, Zhang MX, MacGill RS, Carroll MC, Cutler JE | Journal of immunology | 2001 |
| Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung | Baumann U, Chouchakova N, Gewecke B, Köhl J, Carroll MC, Schmidt RE, Gessner JE | Journal of immunology | 2001 |
| The role of complement in inflammation and adaptive immunity | Barrington R, Zhang M, Fischer M, Carroll MC | Immunological reviews | 2001 |
| Complement facilitates early prion pathogenesis | Klein MA, Kaeser PS, Schwarz P, Weyd H, Xenarios I, Zinkernagel RM, Carroll MC, Verbeek JS, Botto M, Walport MJ, Molina H, Kalinke U, Acha-Orbea H, Aguzzi A | Nature medicine | 2001 |
| A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation | Gommerman JL, Oh DY, Zhou X, Tedder TF, Maurer M, Galli SJ, Carroll MC | Journal of immunology | 2000 |
| Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure | Cunningham PN, Holers VM, Alexander JJ, Guthridge JM, Carroll MC, Quigg RJ | Kidney international | 2000 |
| A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo | Taylor PR, Carugati A, Fadok VA, Cook HT, Andrews M, Carroll MC, Savill JS, Henson PM, Botto M, Walport MJ | The Journal of experimental medicine | 2000 |
| Mouse complement components C4 and Slp act synergistically in a homologous hemolytic C4 assay | Beurskens FJ, Tosi M, Shiroisho T, Robins DM, Carroll MC, van Dijk H | European journal of immunology | 2000 |
| Humoral immune responses in Cr2-/- mice: enhanced affinity maturation but impaired antibody persistence | Chen Z, Koralov SB, Gendelman M, Carroll MC, Kelsoe G | Journal of immunology | 2000 |
| A protective role for innate immunity in autoimmune disease | Carroll MC | Clinical immunology | 2000 |
| Negative selection of B lymphocytes: a novel role for innate immunity | Gommerman JL, Carroll MC | Immunological reviews | 2000 |
| The role of complement in B cell activation and tolerance | Carroll MC | Advances in immunology | 2000 |
| The role of complement receptors CD21/CD35 in positive selection of B-1 cells | Reid RR, Woodcock S, Prodeus AP, Austen J, Kobzik L, Hechtman H, Moore FD Jr, Carroll MC | Current topics in microbiology and immunology | 2000 |
| Regulation of B lymphocyte responses to foreign and self-antigens by the CD19/CD21 complex | Fearon DT, Carroll MC | Annual review of immunology | 2000 |
| Humoral response to herpes simplex virus is complement-dependent | Da Costa XJ, Brockman MA, Alicot E, Ma M, Fischer MB, Zhou X, Knipe DM, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 1999 |
| Protective T cell-independent antiviral antibody responses are dependent on complement | Ochsenbein AF, Pinschewer DD, Odermatt B, Carroll MC, Hengartner H, Zinkernagel RM | The Journal of experimental medicine | 1999 |
| Beta-glucan, a specific biologic response modifier that uses antibodies to target tumors for cytotoxic recognition by leukocyte complement receptor type 3 (CD11b/CD18) | Yan J, Vetvicka V, Xia Y, Coxon A, Carroll MC, Mayadas TN, Ross GD | Journal of immunology | 1999 |
| SAP-less chromatin triggers systemic lupus erythematosus | Paul E, Carroll MC | Nature medicine | 1999 |
| Intestinal reperfusion injury is mediated by IgM and complement | Williams JP, Pechet TT, Weiser MR, Reid R, Kobzik L, Moore FD Jr, Carroll MC, Hechtman HB | Journal of applied physiology | 1999 |
| Innate immunity | Carroll MC, Janeway CA | Current opinion in immunology | 1999 |
| Corneal transplantation in antibody-deficient hosts | Goslings WR, Yamada J, Dana MR, Streilein JW, van Beelen E, Prodeus AP, Carroll MC, Jager MJ | Investigative ophthalmology & visual science | 1999 |
| A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection | Boes M, Prodeus AP, Schmidt T, Carroll MC, Chen J | The Journal of experimental medicine | 1998 |
| A critical role for complement in maintenance of self-tolerance | Prodeus AP, Goerg S, Shen LM, Pozdnyakova OO, Chu L, Alicot EM, Goodnow CC, Carroll MC | Immunity | 1998 |
| Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria | Hébert MJ, Takano T, Papayianni A, Rennke HG, Minto A, Salant DJ, Carroll MC, Brady HR | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | 1998 |
| Evidence for an important interaction between a complement-derived CD21 ligand on follicular dendritic cells and CD21 on B cells in the initiation of IgG responses | Qin D, Wu J, Carroll MC, Burton GF, Szakal AK, Tew JG | Journal of immunology | 1998 |
| CD21/CD35 in B cell activation | Carroll MC | Seminars in immunology | 1998 |
| The lupus paradox | Carroll MC | Nature genetics | 1998 |
| A small molecular weight factor in aqueous humor acts on C1q to prevent antibody-dependent complement activation | Goslings WR, Prodeus AP, Streilein JW, Carroll MC, Jager MJ, Taylor AW | Investigative ophthalmology & visual science | 1998 |
| Dependence of germinal center B cells on expression of CD21/CD35 for survival | Fischer MB, Goerg S, Shen L, Prodeus AP, Goodnow CC, Kelsoe G, Carroll MC | Science | 1998 |
| Activated complement component 3 (C3) is required for ultraviolet induction of immunosuppression and antigenic tolerance | Hammerberg C, Katiyar SK, Carroll MC, Cooper KD | The Journal of experimental medicine | 1998 |
| Local synthesis of C3 within the splenic lymphoid compartment can reconstitute the impaired immune response in C3-deficient mice | Fischer MB, Ma M, Hsu NC, Carroll MC | Journal of immunology | 1998 |
| Immune complex glomerulonephritis in C4- and C3-deficient mice | Quigg RJ, Lim A, Haas M, Alexander JJ, He C, Carroll MC | Kidney international | 1998 |
| Linkages of innate and adaptive immunity | Carroll MC, Prodeus AP | Current opinion in immunology | 1998 |
| The role of complement and complement receptors in induction and regulation of immunity | Carroll MC | Annual review of immunology | 1998 |
| A role for Mac-1 (CDIIb/CD18) in immune complex-stimulated neutrophil function in vivo: Mac-1 deficiency abrogates sustained Fcgamma receptor-dependent neutrophil adhesion and complement-dependent proteinuria in acute glomerulonephritis | Tang T, Rosenkranz A, Assmann KJ, Goodman MJ, Gutierrez-Ramos JC, Carroll MC, Cotran RS, Mayadas TN | The Journal of experimental medicine | 1997 |
| Protection against anti-glomerular basement membrane (GBM)-mediated nephritis in C3- and C4-deficient mice | Sheerin NS, Springall T, Carroll MC, Hartley B, Sacks SH | Clinical and experimental immunology | 1997 |
| Impaired mast cell-dependent natural immunity in complement C3-deficient mice | Prodeus AP, Zhou X, Maurer M, Galli SJ, Carroll MC | Nature | 1997 |
| Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway | Weiser MR, Pechet TT, Williams JP, Ma M, Frenette PS, Moore FD, Kobzik L, Hines RO, Wagner DD, Carroll MC, Hechtman HB | Journal of applied physiology | 1997 |
| Increased susceptibility to endotoxin shock in complement C3- and C4-deficient mice is corrected by C1 inhibitor replacement | Fischer MB, Prodeus AP, Nicholson-Weller A, Ma M, Murrow J, Reid RR, Warren HB, Lage AL, Moore FD Jr, Rosen FS, Carroll MC | Journal of immunology | 1997 |
| Endotoxin shock in antibody-deficient mice: unraveling the role of natural antibody and complement in the clearance of lipopolysaccharide | Reid RR, Prodeus AP, Khan W, Hsu T, Rosen FS, Carroll MC | Journal of immunology | 1997 |
| Complement and the immune response | Carroll MC, Fischer MB | Current opinion in immunology | 1997 |
| Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice | Sylvestre D, Clynes R, Ma M, Warren H, Carroll MC, Ravetch JV | The Journal of experimental medicine | 1996 |
| The route of antigen entry determines the requirement for L-selectin during immune responses | Catalina MD, Carroll MC, Arizpe H, Takashima A, Estess P, Siegelman MH | The Journal of experimental medicine | 1996 |
| Regulation of the B cell response to T-dependent antigens by classical pathway complement | Fischer MB, Ma M, Goerg S, Zhou X, Xia J, Finco O, Han S, Kelsoe G, Howard RG, Rothstein TL, Kremmer E, Rosen FS, Carroll MC | Journal of immunology | 1996 |
| Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement | Weiser MR, Williams JP, Moore FD Jr, Kobzik L, Ma M, Hechtman HB, Carroll MC | The Journal of experimental medicine | 1996 |
| Antibody response to a T-dependent antigen requires B cell expression of complement receptors | Croix DA, Ahearn JM, Rosengard AM, Han S, Kelsoe G, Ma M, Carroll MC | The Journal of experimental medicine | 1996 |
| Neutral endopeptidase modulates septic shock | Lu B, Gerard NP, Kolakowski LF Jr, Finco O, Carroll MC, Gerard C | Annals of the New York Academy of Sciences | 1996 |
| Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen | Ahearn JM, Fischer MB, Croix D, Goerg S, Ma M, Xia J, Zhou X, Howard RG, Rothstein TL, Carroll MC | Immunity | 1996 |
| Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity | Wessels MR, Butko P, Ma M, Warren HB, Lage AL, Carroll MC | Proceedings of the National Academy of Sciences of the United States of America | 1995 |
| Neutral endopeptidase modulation of septic shock | Lu B, Gerard NP, Kolakowski LF Jr, Bozza M, Zurakowski D, Finco O, Carroll MC, Gerard C | The Journal of experimental medicine | 1995 |
| Structure and genetics of the partially duplicated gene RP located immediately upstream of the complement C4A and the C4B genes in the HLA class III region, Molecular cloning, exon-intron structure, composite retroposon, and breakpoint of gene duplication | Shen L, Wu LC, Sanlioglu S, Chen R, Mendoza AR, Dangel AW, Carroll MC, Zipf WB, Yu CY | The Journal of biological chemistry | 1994 |
| The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates | Dangel AW, Mendoza AR, Baker BJ, Daniel CM, Carroll MC, Wu LC, Yu CY | Immunogenetics | 1994 |
| Identification of a major binding site for complement C3 on the IgG1 heavy chain | Shohet JM, Pemberton P, Carroll MC | The Journal of biological chemistry | 1993 |
| A single arginine to tryptophan interchange at beta-chain residue 458 of human complement component C4 accounts for the defect in classical pathway C5 convertase activity of allotype C4A6, Implications for the location of a C5 binding site in C4 | Ebanks RO, Jaikaran AS, Carroll MC, Anderson MJ, Campbell RD, Isenman DE | Journal of immunology | 1992 |
| Covalent binding of C3b to C4b within the classical complement pathway C5 convertase, Determination of amino acid residues involved in ester linkage formation | Kim YU, Carroll MC, Isenman DE, Nonaka M, Pramoonjago P, Takeda J, Inoue K, Kinoshita T | The Journal of biological chemistry | 1992 |
| Structural differences between the two human complement C4 isotypes affect the humoral immune response | Finco O, Li S, Cuccia M, Rosen FS, Carroll MC | The Journal of experimental medicine | 1992 |
| Localization of the human complement component C3 binding site on the IgG heavy chain | Shohet JM, Bergamaschini L, Davis AE, Carroll MC | The Journal of biological chemistry | 1991 |
| Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A | Carroll MC, Fathallah DM, Bergamaschini L, Alicot EM, Isenman DE | Proceedings of the National Academy of Sciences of the United States of America | 1990 |
| Molecular characterization of sialophorin (CD43), the lymphocyte surface sialoglycoprotein defective in Wiskott-Aldrich syndrome | Shelley CS, Remold-O'Donnell E, Davis AE 3rd, Bruns GA, Rosen FS, Carroll MC, Whitehead AS | Proceedings of the National Academy of Sciences of the United States of America | 1989 |
| A previously undetected MHC gene with an unusual periodic structure | Lévi-Strauss M, Carroll MC, Steinmetz M, Meo T | Science | 1988 |
| Organization of the genes encoding complement receptors type 1 and 2, decay-accelerating factor, and C4-binding protein in the RCA locus on human chromosome 1 | Carroll MC, Alicot EM, Katzman PJ, Klickstein LB, Smith JA, Fearon DT | The Journal of experimental medicine | 1988 |
| Linkage map of the human major histocompatibility complex including the tumor necrosis factor genes | Carroll MC, Katzman P, Alicot EM, Koller BH, Geraghty DE, Orr HT, Strominger JL, Spies T | Proceedings of the National Academy of Sciences of the United States of America | 1987 |
| Heterogeneity in the structural basis of the human complement C4A null allele (C4A Q0) as revealed by HindIII restriction fragment length polymorphism analysis | Uring-Lambert B, Vegnaduzzi N, Carroll MC, Tongio MM, Goetz J, Hauptmann G | FEBS letters | 1987 |
| Molecular characterization of the HLA-linked steroid 21-hydroxylase B gene from an individual with congenital adrenal hyperplasia | Rodrigues NR, Dunham I, Yu CY, Carroll MC, Porter RR, Campbell RD | The EMBO journal | 1987 |
| Molecular genetics of the fourth component of human complement | Carroll MC | Federation proceedings | 1987 |
| Polymorphism and molecular genetics of human C4 | Carroll MC, Alper CA | British medical bulletin | 1987 |
| DNA polymorphism of human HLA-linked complement C4 allotypes, including C4 null alleles, in the Finnish population | Partanen J, Peltonen L, Koskimies S, Carroll MC | Human heredity | 1987 |
| Polymorphism of the human complement C4 and steroid 21-hydroxylase genes, Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants | Schneider PM, Carroll MC, Alper CA, Rittner C, Whitehead AS, Yunis EJ, Colten HR | The Journal of clinical investigation | 1986 |
| Deletion of the steroid 21-hydroxylase and complement C4 genes in congenital adrenal hyperplasia | Rumsby G, Carroll MC, Porter RR, Grant DB, Hjelm M | Journal of medical genetics | 1986 |
| Molecular genetics of the fourth component of human complement | Carroll MC, Palsdottir A, Belt KT, Yu CY | Biochemical Society symposium | 1986 |
| The molecular genetics of components of complement | Campbell RD, Carroll MC, Porter RR | Advances in immunology | 1986 |
| Molecular genetics of the fourth component of human complement and steroid 21-hydroxylase | Carroll MC, Belt KT, Palsdottir A, Yu Y | Immunological reviews | 1985 |
| Deletion of complement C4 and steroid 21-hydroxylase genes in the HLA class III region | Carroll MC, Palsdottir A, Belt KT, Porter RR | The EMBO journal | 1985 |
| Mapping of steroid 21-hydroxylase genes adjacent to complement component C4 genes in HLA, the major histocompatibility complex in man | Carroll MC, Campbell RD, Porter RR | Proceedings of the National Academy of Sciences of the United States of America | 1985 |
| Polymorphism of human complement component C4 | Belt KT, Yu CY, Carroll MC, Porter RR | Immunogenetics | 1985 |
| Localization of C4 genes within the HLA complex by molecular genotyping | Robinson MA, Carroll MC, Johnson AH, Hartzman RJ, Belt KT, Kindt TJ | Immunogenetics | 1985 |
| Structure and organization of the C4 genes | Carroll MC, Belt T, Palsdottir A, Porter RR | Philosophical transactions of the Royal Society of London, Series B, Biological sciences | 1984 |
| The structural basis of the multiple forms of human complement component C4 | Belt KT, Carroll MC, Porter RR | Cell | 1984 |
| A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B | Carroll MC, Campbell RD, Bentley DR, Porter RR | Nature | 1984 |
| Correlation between a DNA restriction fragment length polymorphism and C4A6 protein | Palsdottir A, Cross SJ, Edwards JH, Carroll MC | Nature | 1983 |
| Cloning of a human complement component C4 gene | Carroll MC, Porter RR | Proceedings of the National Academy of Sciences of the United States of America | 1983 |
| Identification of H-2-controlled structural variants of the murine Slp protein and demonstration of cis-regulation of its expression | Parker KL, Carroll MC, Shreffler DC, Capra JD | Journal of immunology | 1981 |
| Structural studies on the murine fourth component of complement (C4), IV, Demonstration that C4 and Slp are encoded by separate loci | Carroll MC, Passmore HC, Capra JD | Journal of immunology | 1980 |
| The enhancement of humoral and cellular immune responses by dimethyldioctadecylammonium bromide | Gordon WC, Prager MD, Carroll MC | Cellular immunology | 1980 |
| Studies on murine Ss protein: demonstration that S region encodes structural gene for fourth component of complement | Carroll MC, Capra JD | Proceedings of the National Academy of Sciences of the United States of America | 1979 |
| Studies on the protein products of murine chromosome 17:a status report | Cook R, Carroll MC, Uhr JW, Vitetta ES, Capra JD | Transplantation proceedings | 1978 |
| Studies on the murine Ss protein: demonstration that the Ss protein is functionally the fourth component of complement | Carroll MC, Capra JD | Proceedings of the National Academy of Sciences of the United States of America | 1978 |